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Effective, Safe, Painless, Non-invasive

Incorporate REAC Technology® into your daily treatments.

Achieve targeted clinical outcomes with systemic benefits through therapeutic interventions that address the originating mechanisms of disorders and diseases. Enhance your patients' quality of life and foster the growth of your professional practice.
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What is REAC Technology?

REAC (Radio Electric Asymmetric Conveyer) Technology® is an innovative technology platform developed in Italy. Through specific hardware and software configurations, it emits highly specialized low-power asymmetric radioelectric fields capable of modulating the functions of specific cell populations targeted by the treatment. The objective is to restore cellular bioelectric equilibrium, promoting tissue self-repair and regeneration processes at the organic level and reorganization of neurotransmission processes at the neurological level.

Main features of REAC Technology®:

  • Endogenous bioelectric modulation: acts on cell membrane potentials, optimizing intercellular communication and metabolic activity.
  • Non-invasive and painless: delivers low-intensity radiofrequency signals without side effects.
  • Multi-application: used in regenerative and restorative medicine, anti-aging, mood and behavioral disorders, postural and motor disorders and pain syndromes.
  • Scientifically validated: supported by peer-reviewed research that demonstrates its effectiveness in tissue repair, stress reduction and cellular rejuvenation.
reac-therapy

How it works

The medical devices of the B.E.N.E. (Bio Enhancer Neuro Enhancer) family, following specific therapeutic protocols, emit controlled asymmetric radioelectric fields that are asymmetrically conveyed to the patient in specific treatment areas through A.C.P. (Asymmetric Conveyer Probe).

These interact with cellular bioelectric activity, stimulating the reorganization of neurotransmission processes altered by trauma, disorders, or pathologies, thereby promoting healing.

Treatments take only a few minutes and are safe, painless, with no side effects. Sessions require at least a one-hour interval between them but can be repeated up to four times within the same day.

This feature facilitates faster patient recovery and minimizes logistical challenges. Simultaneously, it enables practitioners to deliver a high volume of treatments daily, leading to greater professional and economic satisfaction.

Application areas

Neurobiological Modulation based on REAC Technology®

neuromodulation-reac

Neuro Psycho Physiopathology

Chronic stress may induce nervous system maladaptation. This dysfunctional state has been linked to a broad spectrum of conditions across various medical fields, such as chronic pain, anxiety, fatigue, sleep disorders, psychosomatic conditions, hyperactivity, and impaired mental health.
Behavioral and Mood Disorders
Specialized REAC protocols modulate weak, asymmetric radiofrequency fields. They interact with endogenous bioelectrical activity to optimize neural circuits regulating mood & behavior, restoring neuro-biophysical balance.
Pain Syndromes
For pain syndromes, REAC treatments modulate endogenous bioelectricity. This optimizes neural processing of pain signals, reducing the perception of pain.
Postural and Motor Disorders
For postural & motor disorders, REAC treatments modulate endogenous bioelectricity via weak radiofields, optimizing neural circuits & neuromuscular communication for improved balance, coordination, and motor control.
Stress-Related Disorders
For stress disorders, REAC treatments optimize the body's adaptive response. Weak radiofields modulate endogenous bioelectricity, normalizing neuro-biophysical function altered by stressors & improving coping mechanisms.
Mental Health
For mental health, REAC technology modulates endogenous bioelectricity with weak radiofields. It targets optimization of neural circuits governing mood, cognition, & stress, improving overall neuro-biophysical function.
Prevention
Treatments based on REAC technology, in addition to acting on targeted objectives, contribute to prevention by promoting functional adaptive neurobiological responses, reducing chronic stress and supporting mental and physical resilience over time.
Application areas

Biological Tissue Modulation based on REAC Technology®

Chronic Inflammation
REAC specialized treatments work by modulating cellular bioelectricity, reducing silent chronic inflammation and restoring the functional balance of tissues with regenerative effects on fibroblasts.
Chronic Tissue Disorders
Chronic tissue disorders involve long-term structural and functional alterations, often causing persistent pain and inflammation.
REAC specialized treatments restores cellular balance, improves tissue quality, and alleviates symptoms, as seen in conditions like lipedema.
Traumatic Injuries
Traumatic injuries result in damage to body tissues, often leading to pain, inflammation, and impaired function.
REAC specialized treatments promotes regeneration, reduces inflammation, and supports faster, more complete recovery.
Circulation
Optimizes cellular signals regulating vascular tone and perfusion. Enhances microcirculation, oxygen/nutrient delivery, reduces inflammation, and supports endothelial function for better vascular health.
Metabolism
Boosts metabolism by enhancing cellular energy production & reducing oxidative stress. Supports cellular adaptation for optimal metabolic balance & function.
Anti-Senescence
REAC Technology Biological Tissue Modulation treatments fight aging by regulating bioelectrical signals, activating longevity proteins, reducing oxidative stress and promoting tissue renewal.
biomodulation-reac

Tissue Physiopathology

Specialized REAC treatments modulate tissue bioelectricity. They aim to restore cellular homeostasis, optimize repair processes, and normalize bioelectrical function altered in pathophysiological conditions.

In addition to facilitating healing, these treatments support cellular health mechanisms, contributing to overall well-being and promoting conditions conducive to an improved healthspan
PubMed-Rinaldi-Fontani-doctors

Scientific evidence

REAC Technology® has been the subject of numerous publications in international scientific journals, validating its therapeutic approach in areas such as:

  • Mood and behavior disorders

  • Postural and motor disorders

  • Treatment of pain syndromes

  • Treatment for repair/regenerative processes

  • Anti-aging and cellular longevity

These scientific findings confirm that REAC Technology® represents an innovative and scientifically validated approach for treating numerous conditions by acting on the fundamental bioelectric mechanisms that regulate cellular and tissue functions.

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Effective, Safe, Painless, Non-invasive

REAC® Technology, developed by the Rinaldi Fontani Institute and powered by ASMED

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Dr. Vania Fontani

dr-vania-fontani-rinaldi-fontani-institute

Dr. Vania Fontani MD, PhD, is a prominent figure in the field of regenerative medicine and neurobiological modulation.

She has dedicated her career to research and the development of innovative technologies for human well-being.

Currently, Dr. Fontani holds the position of Scientific Director at the Rinaldi Fontani Institute in Florence, where she leads the Department of Regenerative Medicine.

In collaboration with Prof. Salvatore Rinaldi, she co-developed the REAC® (Radio Electric Asymmetric Conveyer) technology, a non-invasive methodology aimed at modulating endogenous bioelectric activity to promote health and well-being.

Her research work is documented in over 60 scientific publications, with a significant impact in the field of neuromodulation and regenerative medicine.
Her experience and expertise make her an ideal speaker for international events focused on innovation and longevity

Learn more:
• Publications: PubMed – Rinaldi S, Fontani V

Prof. Salvatore Rinaldi

dr-salvatore-rinaldi-rinaldi-fontani-institu

Physician and researcher, pioneer in neurobiological modulation, regenerative medicine, and anti-senescence therapies Scientific Director – Rinaldi Fontani Institute, Florence, Italy
ORCID: 0000-0002-8961-6316

Profile and Mission

Salvatore Rinaldi is an internationally recognized innovator for his groundbreaking
contribution to the study and clinical application of neurobiological modulation using
asymmetrically conveyed radio-electric signals (REAC). His work has redefined the
boundaries of regenerative medicine and longevity, demonstrating how optimizing
endogenous bioelectrical activity can promote cellular reprogramming, recovery of
compromised functions, and the prevention of age-related decline.

 

Research Milestones

Rinaldi’s research has opened new frontiers in the understanding and treatment of
neurodegenerative diseases and cellular aging processes. Among his most significant
contributions:


Regenerative Medicine:

  • Direct cellular reprogramming through epigenetic modulation of
    endogenous bioelectrical activity with REAC technology.
  • Radiofrequency energy loop primes cardiac, neuronal, and skeletal muscle
    differentiation in mouse embryonic stem cells: a new tool for improving tissue
    regeneration. Cell Transplant. 2012;21(6):1225-33. doi: 10.3727/096368911X600966.
  • Radio electric conveyed fields directly reprogram human dermal skin fibroblasts
    toward cardiac, neuronal, and skeletal muscle-like lineages. Cell Transplant.
    2013;22(7):1227-35. doi: 10.3727/096368912X657297.
  • Neurological morphofunctional differentiation induced by REAC technology in PC12. A
    neuro protective model for Parkinson's disease. Sci Rep. 2015 May 15:5:10439. doi:
    10.1038/srep10439.

Anti-Senescence and Longevity:

  • REAC technology and hyaluron synthase 2, an interesting network to slow down stem
    cell senescence. Sci Rep. 2016 Jun 24:6:28682. doi: 10.1038/srep28682.
  • Stem cell senescence. Effects of REAC technology on telomerase-independent and
    telomerase-dependent pathways. Sci Rep. 2014 Sep 16:4:6373. doi:
    10.1038/srep06373.
  • Anti-senescence efficacy of radio-electric asymmetric conveyer technology. Age
    (Dordr). 2014 Feb;36(1):9-20. doi: 10.1007/s11357-013-9537-8.

Neurodegenerative Diseases – Efficacy of REAC Technology in Alzheimer’s and
Neurodegeneration Models:

  • REAC technology modifies pathological neuroinflammation and motor behaviour in an
    Alzheimer's disease mouse model. Sci Rep. 2016 Oct 24:6:35719. doi:
    10.1038/srep35719.
  • Radio Electric Asymmetric Conveyer Technology Modulates Neuroinflammation in a
    Mouse Model of Neurodegeneration. Neurosci Bull. 2018 Apr;34(2):270-282. doi:
    10.1007/s12264-017-0188-0

Scientific Vision

Salvatore Rinaldi’s work demonstrates that bioelectrical modulation is not merely a
theoretical concept, but a concrete and reproducible therapeutic strategy to counteract
aging, support cellular repair processes, and prevent tissue degeneration.

Learn more:
• ORCID Profile: 0000-0002-8961-6316
• Publications: PubMed – Rinaldi S, Fontani V