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Reac Technology® Featured in Il Sole 24 Ore: The Future of Regenerative Medicine is Now

Il Sole 24 Ore, Italy’s leading financial newspaper, covers how REAC technology is revolutionizing the treatment of headaches, depression, and stroke recovery.

  • October 1, 2025
il-sole-24-ore-reac-technology-headaches-migraines-post-stroke

Reac Technology® Featured in Leading Italian Newspaper Il Sole 24 Ore: How Radioelectric Fields Are Revolutionizing the Treatment of Headaches, Depression, and Post-Stroke Conditions

We are proud to announce that our groundbreaking technology has been featured in a prestigious article by Il Sole 24 Ore, one of Italy’s most authoritative financial and economic newspapers. The article, titled “A radioelectric field to treat headaches, depression, and post-stroke effects,” highlights the revolutionary potential of REAC technology in the field of regenerative medicine.

The feature details how this technology, based on the interaction between very low-intensity radioelectric fields and the body’s cells, is pioneering new frontiers in the treatment of complex and widespread pathologies. This non-invasive approach is designed to optimize the body’s natural self-repair and cellular regeneration processes.

The article emphasizes the clinical applications of our technology, focusing particularly on the promising results achieved in treating:

  • Chronic headaches and migraines
  • Depressive disorders
  • Functional recovery in post-stroke patients

This significant publication is a distinguished acknowledgment of the research and development we have passionately pursued for years. Seeing our scientific discoveries and their practical applications featured in a publication of Il Sole 24 Ore’s caliber is a source of immense pride and reinforces our commitment to advancing innovation for the health and well-being of people worldwide.

We invite our readers, partners, and the scientific community to read the full article to learn more about how REAC technology is shaping a new paradigm in medicine.

Read the full article on Il Sole 24 Ore: A radioelectric field to treat headaches, depression, and post-stroke effects

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Dr. Vania Fontani

dr-vania-fontani-rinaldi-fontani-institute

Dr. Vania Fontani MD, PhD, is a prominent figure in the field of regenerative medicine and neurobiological modulation.

She has dedicated her career to research and the development of innovative technologies for human well-being.

Currently, Dr. Fontani holds the position of Scientific Director at the Rinaldi Fontani Institute in Florence, where she leads the Department of Regenerative Medicine.

In collaboration with Prof. Salvatore Rinaldi, she co-developed the REAC® (Radio Electric Asymmetric Conveyer) technology, a non-invasive methodology aimed at modulating endogenous bioelectric activity to promote health and well-being.

Her research work is documented in over 60 scientific publications, with a significant impact in the field of neuromodulation and regenerative medicine.
Her experience and expertise make her an ideal speaker for international events focused on innovation and longevity

Learn more:
• Publications: PubMed – Rinaldi S, Fontani V

Prof. Salvatore Rinaldi

dr-salvatore-rinaldi-rinaldi-fontani-institu

Physician and researcher, pioneer in neurobiological modulation, regenerative medicine, and anti-senescence therapies Scientific Director – Rinaldi Fontani Institute, Florence, Italy
ORCID: 0000-0002-8961-6316

Profile and Mission

Salvatore Rinaldi is an internationally recognized innovator for his groundbreaking
contribution to the study and clinical application of neurobiological modulation using
asymmetrically conveyed radio-electric signals (REAC). His work has redefined the
boundaries of regenerative medicine and longevity, demonstrating how optimizing
endogenous bioelectrical activity can promote cellular reprogramming, recovery of
compromised functions, and the prevention of age-related decline.

 

Research Milestones

Rinaldi’s research has opened new frontiers in the understanding and treatment of
neurodegenerative diseases and cellular aging processes. Among his most significant
contributions:


Regenerative Medicine:

  • Direct cellular reprogramming through epigenetic modulation of
    endogenous bioelectrical activity with REAC technology.
  • Radiofrequency energy loop primes cardiac, neuronal, and skeletal muscle
    differentiation in mouse embryonic stem cells: a new tool for improving tissue
    regeneration. Cell Transplant. 2012;21(6):1225-33. doi: 10.3727/096368911X600966.
  • Radio electric conveyed fields directly reprogram human dermal skin fibroblasts
    toward cardiac, neuronal, and skeletal muscle-like lineages. Cell Transplant.
    2013;22(7):1227-35. doi: 10.3727/096368912X657297.
  • Neurological morphofunctional differentiation induced by REAC technology in PC12. A
    neuro protective model for Parkinson's disease. Sci Rep. 2015 May 15:5:10439. doi:
    10.1038/srep10439.

Anti-Senescence and Longevity:

  • REAC technology and hyaluron synthase 2, an interesting network to slow down stem
    cell senescence. Sci Rep. 2016 Jun 24:6:28682. doi: 10.1038/srep28682.
  • Stem cell senescence. Effects of REAC technology on telomerase-independent and
    telomerase-dependent pathways. Sci Rep. 2014 Sep 16:4:6373. doi:
    10.1038/srep06373.
  • Anti-senescence efficacy of radio-electric asymmetric conveyer technology. Age
    (Dordr). 2014 Feb;36(1):9-20. doi: 10.1007/s11357-013-9537-8.

Neurodegenerative Diseases – Efficacy of REAC Technology in Alzheimer’s and
Neurodegeneration Models:

  • REAC technology modifies pathological neuroinflammation and motor behaviour in an
    Alzheimer's disease mouse model. Sci Rep. 2016 Oct 24:6:35719. doi:
    10.1038/srep35719.
  • Radio Electric Asymmetric Conveyer Technology Modulates Neuroinflammation in a
    Mouse Model of Neurodegeneration. Neurosci Bull. 2018 Apr;34(2):270-282. doi:
    10.1007/s12264-017-0188-0

Scientific Vision

Salvatore Rinaldi’s work demonstrates that bioelectrical modulation is not merely a
theoretical concept, but a concrete and reproducible therapeutic strategy to counteract
aging, support cellular repair processes, and prevent tissue degeneration.

Learn more:
• ORCID Profile: 0000-0002-8961-6316
• Publications: PubMed – Rinaldi S, Fontani V