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Radio Electric Asymmetrically Conveyed Fields

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Start using REAC® Technology for measurable, lasting results.

Through non-invasive treatments powered by REAC® Technology, the body's endogenous bioelectrical activity is optimized, resulting in real and durable effects.
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What is

REAC® Technology, developed by the Rinaldi Fontani Institute and powered by ASMED® is an innovation in the fields of neuromodulation and biomodulation.

It is based on the restoration of altered endogenous bioelectrical activity, which is essential for cellular and neurological physiology, and may be disrupted by various factors, including epigenetic changes.

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How it works

REAC® uses very low-intensity radio electric fields conducted asymmetrically, not to inject energy into tissues, but to interact with abnormalities in the cells' endogenous bioelectrical activity.

This interaction induces autologous ionic microcurrents, which play a crucial role in the functional reorganization of neural networks a central element in the understanding and treatment of various neurological and behavioral disorders. In biomodulation protocols, these effects manifest at multiple levels, from functional reorganization (including epigenetic levels) to the recovery of altered physiological dynamics, such as inflammation, microcirculation, and metabolism.

Cellular reprogramming and differentiation processes represent an exclusive and advanced area of REAC® regenerative medicine protocols, positioning them as high-level therapeutic tools.

Comparison with Other Technologies

REAC® is often mistakenly grouped with other neuromodulation or physiotherapy devices. However, it possesses unique characteristics, particularly in its mechanism of action: no direct current or magnetic field is applied, and it selectively modulates endogenous bioelectrical imbalances.
Feratures REAC® TMS tDCS DBS TENS/CAR
Invasiveness Non-invasive No No Yes No
Type of Energy Asymmetric radio electric Magnetic fields Direct current Implanted electrical Alternating current
Application Scope Multisystemic Psychiatric Experimental Parkinson's, DOC Local analgesia
Adverse Effect None reported Mild Mild Potentially severe Occasional skin effects
None of the technologies compared selectively modulate endogenous bioelectrical imbalances like REAC®, making it a truly original therapeutic proposal.

REAC® protocols do not aim to replace necessary treatments, nor are they incompatible with them. When applied appropriately, they can integrate with pharmacological and other therapeutic approaches and even enhance their effectiveness by improving the organism’s adaptive responses.
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Effective, Safe, Painless, Non-invasive

REAC® Technology, developed by the Rinaldi Fontani Institute and powered by ASMED

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Dr. Vania Fontani

dr-vania-fontani-rinaldi-fontani-institute

Dr. Vania Fontani MD, PhD, is a prominent figure in the field of regenerative medicine and neurobiological modulation.

She has dedicated her career to research and the development of innovative technologies for human well-being.

Currently, Dr. Fontani holds the position of Scientific Director at the Rinaldi Fontani Institute in Florence, where she leads the Department of Regenerative Medicine.

In collaboration with Prof. Salvatore Rinaldi, she co-developed the REAC® (Radio Electric Asymmetric Conveyer) technology, a non-invasive methodology aimed at modulating endogenous bioelectric activity to promote health and well-being.

Her research work is documented in over 60 scientific publications, with a significant impact in the field of neuromodulation and regenerative medicine.
Her experience and expertise make her an ideal speaker for international events focused on innovation and longevity

Learn more:
• Publications: PubMed – Rinaldi S, Fontani V

Prof. Salvatore Rinaldi

dr-salvatore-rinaldi-rinaldi-fontani-institu

Physician and researcher, pioneer in neurobiological modulation, regenerative medicine, and anti-senescence therapies Scientific Director – Rinaldi Fontani Institute, Florence, Italy
ORCID: 0000-0002-8961-6316

Profile and Mission

Salvatore Rinaldi is an internationally recognized innovator for his groundbreaking
contribution to the study and clinical application of neurobiological modulation using
asymmetrically conveyed radio-electric signals (REAC). His work has redefined the
boundaries of regenerative medicine and longevity, demonstrating how optimizing
endogenous bioelectrical activity can promote cellular reprogramming, recovery of
compromised functions, and the prevention of age-related decline.

 

Research Milestones

Rinaldi’s research has opened new frontiers in the understanding and treatment of
neurodegenerative diseases and cellular aging processes. Among his most significant
contributions:


Regenerative Medicine:

  • Direct cellular reprogramming through epigenetic modulation of
    endogenous bioelectrical activity with REAC technology.
  • Radiofrequency energy loop primes cardiac, neuronal, and skeletal muscle
    differentiation in mouse embryonic stem cells: a new tool for improving tissue
    regeneration. Cell Transplant. 2012;21(6):1225-33. doi: 10.3727/096368911X600966.
  • Radio electric conveyed fields directly reprogram human dermal skin fibroblasts
    toward cardiac, neuronal, and skeletal muscle-like lineages. Cell Transplant.
    2013;22(7):1227-35. doi: 10.3727/096368912X657297.
  • Neurological morphofunctional differentiation induced by REAC technology in PC12. A
    neuro protective model for Parkinson's disease. Sci Rep. 2015 May 15:5:10439. doi:
    10.1038/srep10439.

Anti-Senescence and Longevity:

  • REAC technology and hyaluron synthase 2, an interesting network to slow down stem
    cell senescence. Sci Rep. 2016 Jun 24:6:28682. doi: 10.1038/srep28682.
  • Stem cell senescence. Effects of REAC technology on telomerase-independent and
    telomerase-dependent pathways. Sci Rep. 2014 Sep 16:4:6373. doi:
    10.1038/srep06373.
  • Anti-senescence efficacy of radio-electric asymmetric conveyer technology. Age
    (Dordr). 2014 Feb;36(1):9-20. doi: 10.1007/s11357-013-9537-8.

Neurodegenerative Diseases – Efficacy of REAC Technology in Alzheimer’s and
Neurodegeneration Models:

  • REAC technology modifies pathological neuroinflammation and motor behaviour in an
    Alzheimer's disease mouse model. Sci Rep. 2016 Oct 24:6:35719. doi:
    10.1038/srep35719.
  • Radio Electric Asymmetric Conveyer Technology Modulates Neuroinflammation in a
    Mouse Model of Neurodegeneration. Neurosci Bull. 2018 Apr;34(2):270-282. doi:
    10.1007/s12264-017-0188-0

Scientific Vision

Salvatore Rinaldi’s work demonstrates that bioelectrical modulation is not merely a
theoretical concept, but a concrete and reproducible therapeutic strategy to counteract
aging, support cellular repair processes, and prevent tissue degeneration.

Learn more:
• ORCID Profile: 0000-0002-8961-6316
• Publications: PubMed – Rinaldi S, Fontani V