reac-technology
Contact us
reac-technology
Contact us
Radio Electric Asymmetrically Conveyed Fields

Three decades devoted to advancing human health

For over 30 years, REAC technology has been developed with unwavering passion and respect for human biology, restoring health by working in harmony with the body’s natural intelligence.

Our Story

REAC® (Radio Electric Asymmetric Conveyer) technology was conceived by physicians and researchers Salvatore Rinaldi and Vania Fontani at the Rinaldi Fontani Institute (in Florence, Italy) and manufactured by ASMED®. Its development is the result of extensive research aimed at understanding the interaction between the environment, epigenetic stress, and the neuro-psycho-physical pathophysiology of the human being.


The need to create REAC® technology emerged from clinical observations of numerous pathological conditions in which the functional and adaptive origin often undetectable with traditional diagnostic tools proved decisive.
The goal was to develop a technology capable of selectively interacting with alterations in the cell’s endogenous bioelectrical activity, in a non-invasive manner, free of side effects, and with a high degree of biological personalization. This approach represents a paradigm shift from traditional forced stimulation or pharmacological methods, positioning REAC® and its specific therapeutic protocols as a truly innovative tool in the realm of precision medicine.

Mission & Value

The future challenge is not safety or efficacy both well-documented but rather the cultural and educational effort needed to understand its scientific foundations and clinical potential. Only greater awareness will allow the full appreciation of REAC® technology’s usefulness in medicine and health.
REAC® use is authorized for physicians, psychologists, rehabilitation therapists, and other health professionals based on the applied protocol and always under medical responsibility. Devices are currently in use at numerous centers across Italy, Brazil, and Europe. Training and certification are offered through specific programs by accredited institutions in collaboration with the Rinaldi Fontani Institute.
The body of preclinical and clinical evidence confirms a strong safety and tolerability profile. Future studies, including multicenter trials, will further enhance understanding of the mechanisms of action and consolidate the role of REAC® technology in contemporary medicine.

reac-technology
Home About News
Contact us
© 2026 REAC® All rights reserved
Privacy Policy Terms of Use and Legal Notice
Manage Cookie Credits

Dr. Vania Fontani

dr-vania-fontani-rinaldi-fontani-institute

Dr. Vania Fontani MD, PhD, is a prominent figure in the field of regenerative medicine and neurobiological modulation.

She has dedicated her career to research and the development of innovative technologies for human well-being.

Currently, Dr. Fontani holds the position of Scientific Director at the Rinaldi Fontani Institute in Florence, where she leads the Department of Regenerative Medicine.

In collaboration with Prof. Salvatore Rinaldi, she co-developed the REAC® (Radio Electric Asymmetric Conveyer) technology, a non-invasive methodology aimed at modulating endogenous bioelectric activity to promote health and well-being.

Her research work is documented in over 60 scientific publications, with a significant impact in the field of neuromodulation and regenerative medicine.
Her experience and expertise make her an ideal speaker for international events focused on innovation and longevity

Learn more:
• Publications: PubMed – Rinaldi S, Fontani V

Prof. Salvatore Rinaldi

dr-salvatore-rinaldi-rinaldi-fontani-institu

Physician and researcher, pioneer in neurobiological modulation, regenerative medicine, and anti-senescence therapies Scientific Director – Rinaldi Fontani Institute, Florence, Italy
ORCID: 0000-0002-8961-6316

Profile and Mission

Salvatore Rinaldi is an internationally recognized innovator for his groundbreaking
contribution to the study and clinical application of neurobiological modulation using
asymmetrically conveyed radio-electric signals (REAC). His work has redefined the
boundaries of regenerative medicine and longevity, demonstrating how optimizing
endogenous bioelectrical activity can promote cellular reprogramming, recovery of
compromised functions, and the prevention of age-related decline.

 

Research Milestones

Rinaldi’s research has opened new frontiers in the understanding and treatment of
neurodegenerative diseases and cellular aging processes. Among his most significant
contributions:


Regenerative Medicine:

  • Direct cellular reprogramming through epigenetic modulation of
    endogenous bioelectrical activity with REAC technology.
  • Radiofrequency energy loop primes cardiac, neuronal, and skeletal muscle
    differentiation in mouse embryonic stem cells: a new tool for improving tissue
    regeneration. Cell Transplant. 2012;21(6):1225-33. doi: 10.3727/096368911X600966.
  • Radio electric conveyed fields directly reprogram human dermal skin fibroblasts
    toward cardiac, neuronal, and skeletal muscle-like lineages. Cell Transplant.
    2013;22(7):1227-35. doi: 10.3727/096368912X657297.
  • Neurological morphofunctional differentiation induced by REAC technology in PC12. A
    neuro protective model for Parkinson's disease. Sci Rep. 2015 May 15:5:10439. doi:
    10.1038/srep10439.

Anti-Senescence and Longevity:

  • REAC technology and hyaluron synthase 2, an interesting network to slow down stem
    cell senescence. Sci Rep. 2016 Jun 24:6:28682. doi: 10.1038/srep28682.
  • Stem cell senescence. Effects of REAC technology on telomerase-independent and
    telomerase-dependent pathways. Sci Rep. 2014 Sep 16:4:6373. doi:
    10.1038/srep06373.
  • Anti-senescence efficacy of radio-electric asymmetric conveyer technology. Age
    (Dordr). 2014 Feb;36(1):9-20. doi: 10.1007/s11357-013-9537-8.

Neurodegenerative Diseases – Efficacy of REAC Technology in Alzheimer’s and
Neurodegeneration Models:

  • REAC technology modifies pathological neuroinflammation and motor behaviour in an
    Alzheimer's disease mouse model. Sci Rep. 2016 Oct 24:6:35719. doi:
    10.1038/srep35719.
  • Radio Electric Asymmetric Conveyer Technology Modulates Neuroinflammation in a
    Mouse Model of Neurodegeneration. Neurosci Bull. 2018 Apr;34(2):270-282. doi:
    10.1007/s12264-017-0188-0

Scientific Vision

Salvatore Rinaldi’s work demonstrates that bioelectrical modulation is not merely a
theoretical concept, but a concrete and reproducible therapeutic strategy to counteract
aging, support cellular repair processes, and prevent tissue degeneration.

Learn more:
• ORCID Profile: 0000-0002-8961-6316
• Publications: PubMed – Rinaldi S, Fontani V