reac-technology
reac-technology

La Repubblica Features REAC® Technology: “An Italian Technology Opens New Perspectives in the Treatment of Autism”

Leading Italian newspaper La Repubblica features REAC® technology, a breakthrough innovation opening new perspectives in autism spectrum disorder treatment

  • September 30, 2025
autism-reac-bwo-rinaldi-fontani-institute

The prestigious Italian national newspaper has dedicated an in-depth feature to our technology, highlighting its revolutionary impact and the new possibilities it offers for patients and their families.

We are proud to share a significant media recognition with our community. La Repubblica, one of Italy’s leading national newspapers, has published an in-depth article shining a spotlight on the transformative potential of our REAC® technology in the treatment of autism spectrum disorders.


The article, titled “Autismo, una tecnologia italiana apre nuove prospettive nel trattamento della patologia” (Autism, an Italian technology opens new perspectives in the treatment of the pathology), explores how our non-invasive approach is offering new hope and tangible results. This feature serves as a meaningful validation of the research and development work we have pursued with passion and scientific rigor for over three decades.

The piece in La Repubblica particularly emphasizes how REAC® technology, conceived by physicians and researchers Salvatore Rinaldi and Vania Fontani, represents a paradigm shift from traditional approaches. The article highlights the ability of our neuromodulation protocols to selectively interact with the bioelectric activity of the nervous system, thereby promoting a process of recovery and rebalancing of neurological functions.


This important journalistic coverage not only acknowledges the efficacy and safety of our technology, which is already extensively documented, but also helps to spread greater awareness about the new frontiers of precision medicine.


We firmly believe that innovation must serve people to concretely improve their quality of life. The attention from such an authoritative news organization inspires us to continue with even greater determination in our mission: to make REAC® Technology accessible to a growing number of patients who can benefit from it.

We invite our entire community, industry professionals, and journalists to read the full article in La Repubblica to learn more about how an Italian technology is opening new horizons in the treatment of autism.


Read the full article on La Repubblica.it
Read the scientific study on Preprints.org

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Dr. Vania Fontani

dr-vania-fontani-rinaldi-fontani-institute

Dr. Vania Fontani MD, PhD, is a prominent figure in the field of regenerative medicine and neurobiological modulation.

She has dedicated her career to research and the development of innovative technologies for human well-being.

Currently, Dr. Fontani holds the position of Scientific Director at the Rinaldi Fontani Institute in Florence, where she leads the Department of Regenerative Medicine.

In collaboration with Prof. Salvatore Rinaldi, she co-developed the REAC® (Radio Electric Asymmetric Conveyer) technology, a non-invasive methodology aimed at modulating endogenous bioelectric activity to promote health and well-being.

Her research work is documented in over 60 scientific publications, with a significant impact in the field of neuromodulation and regenerative medicine.
Her experience and expertise make her an ideal speaker for international events focused on innovation and longevity

Learn more:
• Publications: PubMed – Rinaldi S, Fontani V

Prof. Salvatore Rinaldi

dr-salvatore-rinaldi-rinaldi-fontani-institu

Physician and researcher, pioneer in neurobiological modulation, regenerative medicine, and anti-senescence therapies Scientific Director – Rinaldi Fontani Institute, Florence, Italy
ORCID: 0000-0002-8961-6316

Profile and Mission

Salvatore Rinaldi is an internationally recognized innovator for his groundbreaking
contribution to the study and clinical application of neurobiological modulation using
asymmetrically conveyed radio-electric signals (REAC). His work has redefined the
boundaries of regenerative medicine and longevity, demonstrating how optimizing
endogenous bioelectrical activity can promote cellular reprogramming, recovery of
compromised functions, and the prevention of age-related decline.

 

Research Milestones

Rinaldi’s research has opened new frontiers in the understanding and treatment of
neurodegenerative diseases and cellular aging processes. Among his most significant
contributions:


Regenerative Medicine:

  • Direct cellular reprogramming through epigenetic modulation of
    endogenous bioelectrical activity with REAC technology.
  • Radiofrequency energy loop primes cardiac, neuronal, and skeletal muscle
    differentiation in mouse embryonic stem cells: a new tool for improving tissue
    regeneration. Cell Transplant. 2012;21(6):1225-33. doi: 10.3727/096368911X600966.
  • Radio electric conveyed fields directly reprogram human dermal skin fibroblasts
    toward cardiac, neuronal, and skeletal muscle-like lineages. Cell Transplant.
    2013;22(7):1227-35. doi: 10.3727/096368912X657297.
  • Neurological morphofunctional differentiation induced by REAC technology in PC12. A
    neuro protective model for Parkinson's disease. Sci Rep. 2015 May 15:5:10439. doi:
    10.1038/srep10439.

Anti-Senescence and Longevity:

  • REAC technology and hyaluron synthase 2, an interesting network to slow down stem
    cell senescence. Sci Rep. 2016 Jun 24:6:28682. doi: 10.1038/srep28682.
  • Stem cell senescence. Effects of REAC technology on telomerase-independent and
    telomerase-dependent pathways. Sci Rep. 2014 Sep 16:4:6373. doi:
    10.1038/srep06373.
  • Anti-senescence efficacy of radio-electric asymmetric conveyer technology. Age
    (Dordr). 2014 Feb;36(1):9-20. doi: 10.1007/s11357-013-9537-8.

Neurodegenerative Diseases – Efficacy of REAC Technology in Alzheimer’s and
Neurodegeneration Models:

  • REAC technology modifies pathological neuroinflammation and motor behaviour in an
    Alzheimer's disease mouse model. Sci Rep. 2016 Oct 24:6:35719. doi:
    10.1038/srep35719.
  • Radio Electric Asymmetric Conveyer Technology Modulates Neuroinflammation in a
    Mouse Model of Neurodegeneration. Neurosci Bull. 2018 Apr;34(2):270-282. doi:
    10.1007/s12264-017-0188-0

Scientific Vision

Salvatore Rinaldi’s work demonstrates that bioelectrical modulation is not merely a
theoretical concept, but a concrete and reproducible therapeutic strategy to counteract
aging, support cellular repair processes, and prevent tissue degeneration.

Learn more:
• ORCID Profile: 0000-0002-8961-6316
• Publications: PubMed – Rinaldi S, Fontani V