We are proud to announce the participation of ASMED® S.r.l. at the Lipedema World Congress 2025, the premier international event dedicated to lipedema, which will be held in Rome from November 5-8, 2025. ASMED® S.r.l., the exclusive manufacturer of medical devices and accessories for REAC® (Radio Electric Asymmetric Conveyer) Technology, will present its innovative solutions at booth 25-27, starting November 6th. Special guests will include the inventors of the technology, Prof. Salvatore Rinaldi and Dr. Vania Fontani from the Rinaldi Fontani Institute in Florence.

A Congress of Global Significance

The Lipedema World Congress represents a unique opportunity to bring together the world’s leading experts and healthcare professionals from various disciplines for an unprecedented multidisciplinary exchange. The event, promoted by the Lipedema World Alliance in collaboration with Fiera Roma, will feature speakers and delegations from over 30 countries.

Congress Presidents

The congress is chaired by three prominent figures in the international scientific community:

• Prof. Sandro Michelini, MD, PhD – Italy
• Prof. Karen L. Herbst, MD, PhD – United States
• Prof. Mojtaba Ghods, MD, PhD – Germany

Program and Venues

The event is structured in two distinct parts:

• November 5 – Pre-Congress
   At the San Giovanni Battista Hospital in Rome, with sessions dedicated to live and recorded surgery, offering participants the opportunity to observe the most advanced surgical techniques for lipedema treatment.
• November 6-8 – Main Congress
   At Fiera di Roma, Hall 10, held in conjunction with Welfair 2025, where the main scientific sessions will take place.

 REAC® Technology: An Innovative Approach to Lipedema

Lipedema is a chronic condition characterized by the abnormal and symmetrical accumulation of adipose tissue, primarily in the lower limbs, accompanied by pain, edema, and chronic inflammation. This condition, which predominantly affects women, is often associated with metabolic syndrome, insulin resistance, and circulatory dysfunctions.

The REAC Biomodulatory Approach

REAC® Technology treatments represent an innovative, non-invasive approach to managing lipedema, based on the modulation of cellular bio-electric activity. Through asymmetrically conveyed radio-electric fields, REAC® Technology acts at a cellular level to restore homeostasis and promote endogenous repair processes.

REAC medical devices, such as the BENE Mod 110, utilize specific tissue optimization protocols that have proven particularly effective for conditions related to lipedema.

REAC Protocols for Lipedema

1. Anti-Inflammatory Anti-Cellulite Treatment (TO-ACT)
   The ACT protocol goes beyond aesthetics to directly address chronic tissue inflammation, a key factor in the pathogenesis of lipedema. Recent studies have shown that this protocol:
   • Reduces systemic and localized inflammation
   • Improves microcirculation and lymphatic drainage
   • Enhances skin elasticity and the biomechanical properties of subcutaneous tissue
   • Promotes tissue repair

2. Circulatory Optimization (TO-CO)
   The CO protocol is essential for addressing the circulatory dysfunctions associated with lipedema:
   • Improves blood flow and tissue perfusion
   • Reduces edema and supports lymphatic drainage
   • Optimizes microcirculation
   • Alleviates the feeling of heaviness in the limbs

3. Metabolic Optimization (TO-MO)
    The MO protocol targets the metabolic dysregulation characteristic of lipedema:
   • Restores cellular metabolic balance
   • Improves energy efficiency
   • Supports weight management
   • Reduces insulin resistance

Scientific Evidence

Recent studies published in peer-reviewed journals have documented significant results in patients with lipedema-related conditions treated with REAC® Technology-based protocols:

• Chronic Pain Reduction: In patients with metabolic syndrome and edema, the combination of ACT, CO, and MO protocols led to a reduction in pain intensity from 10/10 to 5/10, eliminating the need for morphine for pain management.
• Improvement in Edema and Circulation: Patients with chronic lower limb edema showed significant reductions in swelling, accompanied by improvements in skin appearance, with decreased erythema and enhanced tissue elasticity.
• Weight Loss and Metabolic Optimization: Treatments facilitated weight loss of up to 7 kg in elderly patients with morbid obesity and metabolic syndrome, with a reduction in abdominal circumference and improved body composition.
• Systemic Benefits: Beyond local improvements, patients reported significant enhancements in sleep quality, mood stability, energy levels, and overall quality of life.

Some freely available studies:

• Radio Electric Asymmetric Conveyer (REAC) Biomodulation for Chronic Pain and Functional Improvement in Rheumatoid Arthritis, Lipedema, and Fibromyalgia: A Case Study on Anti-inflammatory, Circulatory, and Metabolic Optimization

• Efficacy of Radio Electric Asymmetric Conveyor (REAC) Anti-inflammatory, Circulatory, and Metabolic Optimization Treatments for Managing Chronic Pain, Edema, and Lipodystrophy in Post-menopausal Women: A Case Series

• Therapeutic Outcomes of Biomodulation With Radio Electric Asymmetric Conveyer (REAC) Technology in an 80-Year-Old Female: A Case Report on Anti-cellulite, Circulatory, and Metabolic Optimization Treatments

Congress Topics Relevant to REAC Technology

The congress program covers numerous aspects of the condition that align perfectly with the applications of REAC technology:

• Pathophysiology and Inflammation: Lipedema and chronic pain, metabolic aspects and systemic inflammation, insulin resistance.
• Circulatory and Lymphatic System: Correlations with the lymphatic system, circulatory dysfunctions, chronic edema.
• Therapeutic Approaches: Conservative treatment, nutritional aspects, innovative non-invasive therapies.

An Integrated and Multidisciplinary Approach

The congress welcomes professionals from diverse medical specialties, including lymphologists, plastic surgeons, angiologists, phlebologists, nutritionists, dermatologists, physiotherapists, and radiologists. This variety of expertise provides the ideal context to present REAC® Technology, which offers an integrative approach complementary to traditional therapies. The presence of patient association representatives underscores the importance of therapeutic solutions that tangibly improve quality of life—a central focus of REAC treatments.

REAC® Technology at the Congress: Booth 25-27

We invite you to visit our booth 25-27 at Fiera di Roma during the congress. Our team of experts will be available to provide:

• Live demonstrations of REAC® Technology
• Presentations of the BENE Mod 110 medical devices
• Discussions on the TO-ACT, CO, and MO protocols for lipedema
• Sharing of clinical case reports and results
• Networking with industry professionals

What We Are Bringing to the Congress

• Technological Innovation: REAC® Technology represents a significant advancement in biomodulation, with an approach that addresses the root causes of the condition, not just the symptoms.
• Clinical Evidence: We will present the latest case reports and published studies documenting the efficacy of REAC protocols in lipedema-related conditions.
• Integrated Approach: Our protocols offer a non-invasive alternative or complement to traditional therapies, with benefits that extend beyond symptomatic relief.
• Safety and Tolerability: REAC treatments are characterized by an excellent safety profile, with no significant adverse effects reported in clinical studies.

 Beyond Treatment: Research and Collaboration

Our participation in the Lipedema World Congress 2025 is also an opportunity to:

• Foster Research Collaborations: Establish new partnerships with international centers of excellence for large-scale controlled clinical trials.
• Share Knowledge: Contribute to the scientific dialogue on new therapeutic frontiers for lipedema.
• Develop Protocols: Collaborate with international experts to further optimize treatment protocols.
• Provide Professional Training: Offer training opportunities on REAC technology to interested healthcare professionals.

The Future of Lipedema Treatment

Lipedema is an often underdiagnosed and undertreated condition affecting millions of women worldwide. The innovative approach of REAC® Technology, which simultaneously addresses inflammation, circulation, and metabolism, represents a promising therapeutic option that can significantly improve patients’ quality of life.

Preliminary studies show encouraging results not only in reducing local symptoms but also in systemically improving metabolic health, circulatory function, and psychological well-being. These multidimensional benefits are particularly relevant for a complex condition like lipedema, which requires an integrated therapeutic approach.

A Personalized Medicine Approach

REAC® Technology fits perfectly within the paradigm of personalized medicine by promoting endogenous repair processes and restoring cellular bio-electric balance. This approach respects the body’s natural physiological mechanisms, supporting them rather than overriding them.

The Lipedema World Congress 2025 is the ideal platform to present this innovation to the international scientific community and gather feedback from leading experts, thereby contributing to the evolution of therapeutic strategies for lipedema.

We Look Forward to Seeing You in Rome

ASMED® S.r.l. invites you to visit booth 25-27 at Fiera di Roma from November 6-8, 2025. We would be delighted to share with you:

• Our experience in applying REAC® Technology
• The latest clinical results
• Future prospects for research and development
• Opportunities for collaboration

Together, we can help advance the understanding and treatment of lipedema, offering patients new hope and effective therapeutic solutions.

For more information about the event, visit the official website: Lipedema World Congress 2025

Visit ASMED® S.r.l.
Innovation for health and well-being: biomodulation with REAC® Technology

📅 November 6-8, 2025
📍 Fiera Roma – Hall 10
🎪 Booth 25-27 

Contact Information
For more information or to schedule a meeting at our booth during the congress, please contact us:
REAC® Technology

See you in Rome to build the future of lipedema treatment together.