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Radio Electric Asymmetrically Conveyed Fields

Medical Protocols

The therapeutic protocols of REAC® technology are designed to deliver selective and biologically personalized bioelectrical modulation, targeting alterations in the bioelectrical gradient to restore the body’s natural functions and enhance overall well-being.
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Exclusive & Effective

REAC® therapeutic protocols are preset and cannot be modified by the operator, the mechanism of action allows for a high degree of biological personalization. The interaction occurs only in areas with bioelectrical abnormalities, enabling precise, selective modulation, free from operator interference. This feature makes REAC® one of the most advanced forms of precision medicine available.
Since the treatment guides the body in recovering its own functions, it is important to clarify that a therapeutic response is virtually always observed. However, the outcome may sometimes differ from expectations not due to ineffectiveness, but because it represents either the maximum result achievable at that time or a step toward further improvement.

Clinical uses

Neurobiological Modulation
Focused on reorganizing neuro-psycho-physical activity, regulating emotional and behavioral states, and modulating stress responses. Includes protocols such as NPO (Neuro Postural Optimization), NPPO (Neuro Psycho Physical Optimization), NPPO-CB (cervico-brachial version), and BWO (Brain Wave Optimization).
Physiological and Structural Biomodulation
Focused on reparative and regenerative processes, the management of pain syndromes, and the optimization of circulatory and metabolic functions. Includes protocols such as TO-ACT (Anti-Cellulite Treatment), TO-CO (Circulatory Optimization), and TO-MO (Metabolic Optimization).
Reparative Medicine
With protocols targeting tissue recovery in cases of muscular, joint, or skin injuries, based on evidence of local and systemic improvements in cell physiology.
Regenerative Medicine
An advanced field of REAC® application, with RGN family protocols that activate physiological processes of cellular reprogramming and differentiation. Clinically used in neurodegenerative and genetic diseases, and longevity programs.
Cardiology
Specific application with EX-RER family protocols aimed at modulating myocardial function, including variants for atrial fibrillation, extrasystoles, and heart failure.
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Effective, Safe, Painless, Non-invasive

REAC® Technology, developed by the Rinaldi Fontani Institute and powered by ASMED

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Dr. Vania Fontani

dr-vania-fontani-rinaldi-fontani-institute

Dr. Vania Fontani MD, PhD, is a prominent figure in the field of regenerative medicine and neurobiological modulation.

She has dedicated her career to research and the development of innovative technologies for human well-being.

Currently, Dr. Fontani holds the position of Scientific Director at the Rinaldi Fontani Institute in Florence, where she leads the Department of Regenerative Medicine.

In collaboration with Prof. Salvatore Rinaldi, she co-developed the REAC® (Radio Electric Asymmetric Conveyer) technology, a non-invasive methodology aimed at modulating endogenous bioelectric activity to promote health and well-being.

Her research work is documented in over 60 scientific publications, with a significant impact in the field of neuromodulation and regenerative medicine.
Her experience and expertise make her an ideal speaker for international events focused on innovation and longevity

Learn more:
• Publications: PubMed – Rinaldi S, Fontani V

Prof. Salvatore Rinaldi

dr-salvatore-rinaldi-rinaldi-fontani-institu

Physician and researcher, pioneer in neurobiological modulation, regenerative medicine, and anti-senescence therapies Scientific Director – Rinaldi Fontani Institute, Florence, Italy
ORCID: 0000-0002-8961-6316

Profile and Mission

Salvatore Rinaldi is an internationally recognized innovator for his groundbreaking
contribution to the study and clinical application of neurobiological modulation using
asymmetrically conveyed radio-electric signals (REAC). His work has redefined the
boundaries of regenerative medicine and longevity, demonstrating how optimizing
endogenous bioelectrical activity can promote cellular reprogramming, recovery of
compromised functions, and the prevention of age-related decline.

 

Research Milestones

Rinaldi’s research has opened new frontiers in the understanding and treatment of
neurodegenerative diseases and cellular aging processes. Among his most significant
contributions:


Regenerative Medicine:

  • Direct cellular reprogramming through epigenetic modulation of
    endogenous bioelectrical activity with REAC technology.
  • Radiofrequency energy loop primes cardiac, neuronal, and skeletal muscle
    differentiation in mouse embryonic stem cells: a new tool for improving tissue
    regeneration. Cell Transplant. 2012;21(6):1225-33. doi: 10.3727/096368911X600966.
  • Radio electric conveyed fields directly reprogram human dermal skin fibroblasts
    toward cardiac, neuronal, and skeletal muscle-like lineages. Cell Transplant.
    2013;22(7):1227-35. doi: 10.3727/096368912X657297.
  • Neurological morphofunctional differentiation induced by REAC technology in PC12. A
    neuro protective model for Parkinson's disease. Sci Rep. 2015 May 15:5:10439. doi:
    10.1038/srep10439.

Anti-Senescence and Longevity:

  • REAC technology and hyaluron synthase 2, an interesting network to slow down stem
    cell senescence. Sci Rep. 2016 Jun 24:6:28682. doi: 10.1038/srep28682.
  • Stem cell senescence. Effects of REAC technology on telomerase-independent and
    telomerase-dependent pathways. Sci Rep. 2014 Sep 16:4:6373. doi:
    10.1038/srep06373.
  • Anti-senescence efficacy of radio-electric asymmetric conveyer technology. Age
    (Dordr). 2014 Feb;36(1):9-20. doi: 10.1007/s11357-013-9537-8.

Neurodegenerative Diseases – Efficacy of REAC Technology in Alzheimer’s and
Neurodegeneration Models:

  • REAC technology modifies pathological neuroinflammation and motor behaviour in an
    Alzheimer's disease mouse model. Sci Rep. 2016 Oct 24:6:35719. doi:
    10.1038/srep35719.
  • Radio Electric Asymmetric Conveyer Technology Modulates Neuroinflammation in a
    Mouse Model of Neurodegeneration. Neurosci Bull. 2018 Apr;34(2):270-282. doi:
    10.1007/s12264-017-0188-0

Scientific Vision

Salvatore Rinaldi’s work demonstrates that bioelectrical modulation is not merely a
theoretical concept, but a concrete and reproducible therapeutic strategy to counteract
aging, support cellular repair processes, and prevent tissue degeneration.

Learn more:
• ORCID Profile: 0000-0002-8961-6316
• Publications: PubMed – Rinaldi S, Fontani V