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Effective, Safe, Painless, Non-invasive

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Developed by medical researchers and Rinaldi Fontani Institute founders Prof. Salvatore Rinaldi and Dr. Vania Fontani, REAC Technology's medical devices are manufactured and certified by ASMED, a company in Scandicci, Florence (Italy).
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Rinaldi Fontani Istitute

The Rinaldi Fontani Institute (IRF) in Florence is an internationally renowned center for medical research and application, founded by Prof. Salvatore Rinaldi and Dr. Vania Fontani. Since its establishment, the IRF has distinguished itself with a pioneering approach to medicine, focused on understanding and modulating the biophysical mechanisms that regulate health and disease. The culmination of decades of research and clinical experimentation conducted within the institute is represented by the invention and development of REAC® (Radio Electric Asymmetric Conveyer) Technology. This innovative and unique technological platform is based on the interaction of weak, asymmetric radiofrequency fields with the body's endogenous bioelectrical activity. Through specific therapeutic protocols, REAC Technology aims to optimize neurotransmission and cellular functionality, offering non-invasive therapeutic solutions for a wide range of disorders, spanning from pain and stress-related syndromes to neurodegenerative diseases and tissue repair processes. The Rinaldi Fontani Institute continues to be the driving force behind the research and evolution of REAC Technology, promoting its clinical application and global dissemination with the goal of improving patients' quality of life through an advanced and personalized medical approach.
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ASMED® company

ASMED, based in Scandicci, Florence (Italy), is a certified company specializing in the manufacturing and certification of advanced medical devices. With a strong commitment to innovation and quality, ASMED plays a crucial role in translating cutting-edge scientific research into tangible therapeutic solutions. The company is particularly recognized for its pivotal role in the production and certification of medical devices based on REAC® (Radio Electric Asymmetric Conveyer) Technology, a groundbreaking platform developed by the Rinaldi Fontani Institute. ASMED ensures that these sophisticated devices meet rigorous international standards for safety and efficacy, meticulously managing the hardware and software configurations for specific therapeutic applications. Through its expertise in medical device engineering and manufacturing, ASMED facilitates the delivery of REAC Technology's unique non-invasive bioregulation and neuromodulation treatments to healthcare professionals and patients worldwide, contributing significantly to the advancement of innovative medical care.
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SONC Association

The Scientific Society of Neuro Psycho Physical Optimization (SONC) is a distinguished organization dedicated to the advancement and dissemination of knowledge in the field of neuro-psycho-physical optimization. Comprising a network of researchers, clinicians, and healthcare professionals, SONC focuses on exploring and promoting innovative therapeutic approaches that address the intricate interplay between neurological, psychological, and physical well-being. A key area of interest and expertise for SONC lies in the research, clinical application, and scientific validation of treatments based on REAC® (Radio Electric Asymmetric Conveyer) Technology. The society actively fosters scientific investigation into the mechanisms and efficacy of REAC Technology across a broad spectrum of conditions, including mood disorders, stress-related syndromes, pain management, and neurodegenerative diseases. Through conferences, publications, and collaborative research projects, SONC aims to establish best practices, share clinical experiences, and expand the understanding of how non-invasive neuromodulation and bioregulation techniques, such as those offered by REAC Technology, can optimize human health and performance. SONC plays a vital role in bridging the gap between scientific discovery and clinical practice, ensuring that advancements in neuro-psycho-physical optimization are accessible and effectively utilized for patient benefit.
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Effective, Safe, Painless, Non-invasive

REAC® Technology, developed by the Rinaldi Fontani Institute and powered by ASMED

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Dr. Vania Fontani

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Dr. Vania Fontani MD, PhD, is a prominent figure in the field of regenerative medicine and neurobiological modulation.

She has dedicated her career to research and the development of innovative technologies for human well-being.

Currently, Dr. Fontani holds the position of Scientific Director at the Rinaldi Fontani Institute in Florence, where she leads the Department of Regenerative Medicine.

In collaboration with Prof. Salvatore Rinaldi, she co-developed the REAC® (Radio Electric Asymmetric Conveyer) technology, a non-invasive methodology aimed at modulating endogenous bioelectric activity to promote health and well-being.

Her research work is documented in over 60 scientific publications, with a significant impact in the field of neuromodulation and regenerative medicine.
Her experience and expertise make her an ideal speaker for international events focused on innovation and longevity

Learn more:
• Publications: PubMed – Rinaldi S, Fontani V

Prof. Salvatore Rinaldi

dr-salvatore-rinaldi-rinaldi-fontani-institu

Physician and researcher, pioneer in neurobiological modulation, regenerative medicine, and anti-senescence therapies Scientific Director – Rinaldi Fontani Institute, Florence, Italy
ORCID: 0000-0002-8961-6316

Profile and Mission

Salvatore Rinaldi is an internationally recognized innovator for his groundbreaking
contribution to the study and clinical application of neurobiological modulation using
asymmetrically conveyed radio-electric signals (REAC). His work has redefined the
boundaries of regenerative medicine and longevity, demonstrating how optimizing
endogenous bioelectrical activity can promote cellular reprogramming, recovery of
compromised functions, and the prevention of age-related decline.

 

Research Milestones

Rinaldi’s research has opened new frontiers in the understanding and treatment of
neurodegenerative diseases and cellular aging processes. Among his most significant
contributions:


Regenerative Medicine:

  • Direct cellular reprogramming through epigenetic modulation of
    endogenous bioelectrical activity with REAC technology.
  • Radiofrequency energy loop primes cardiac, neuronal, and skeletal muscle
    differentiation in mouse embryonic stem cells: a new tool for improving tissue
    regeneration. Cell Transplant. 2012;21(6):1225-33. doi: 10.3727/096368911X600966.
  • Radio electric conveyed fields directly reprogram human dermal skin fibroblasts
    toward cardiac, neuronal, and skeletal muscle-like lineages. Cell Transplant.
    2013;22(7):1227-35. doi: 10.3727/096368912X657297.
  • Neurological morphofunctional differentiation induced by REAC technology in PC12. A
    neuro protective model for Parkinson's disease. Sci Rep. 2015 May 15:5:10439. doi:
    10.1038/srep10439.

Anti-Senescence and Longevity:

  • REAC technology and hyaluron synthase 2, an interesting network to slow down stem
    cell senescence. Sci Rep. 2016 Jun 24:6:28682. doi: 10.1038/srep28682.
  • Stem cell senescence. Effects of REAC technology on telomerase-independent and
    telomerase-dependent pathways. Sci Rep. 2014 Sep 16:4:6373. doi:
    10.1038/srep06373.
  • Anti-senescence efficacy of radio-electric asymmetric conveyer technology. Age
    (Dordr). 2014 Feb;36(1):9-20. doi: 10.1007/s11357-013-9537-8.

Neurodegenerative Diseases – Efficacy of REAC Technology in Alzheimer’s and
Neurodegeneration Models:

  • REAC technology modifies pathological neuroinflammation and motor behaviour in an
    Alzheimer's disease mouse model. Sci Rep. 2016 Oct 24:6:35719. doi:
    10.1038/srep35719.
  • Radio Electric Asymmetric Conveyer Technology Modulates Neuroinflammation in a
    Mouse Model of Neurodegeneration. Neurosci Bull. 2018 Apr;34(2):270-282. doi:
    10.1007/s12264-017-0188-0

Scientific Vision

Salvatore Rinaldi’s work demonstrates that bioelectrical modulation is not merely a
theoretical concept, but a concrete and reproducible therapeutic strategy to counteract
aging, support cellular repair processes, and prevent tissue degeneration.

Learn more:
• ORCID Profile: 0000-0002-8961-6316
• Publications: PubMed – Rinaldi S, Fontani V